Maxictam®-AF

Maxictam^®-AF

Maxictam^®-AF is a unique combination of Cefepime and Sulbactam for empiric treatment of nosocomial infections caused by multidrug-resistant pathogens.

General properties of Maxictam^®-AF

Drug class: inhibitor-protected IV generation cephalosporin;
Composition: cefepime 1000 mg + sulbactam 1000 mg;
Presentation: powder for the preparation of a solution for intravenous and intramuscular administration;
Indications: infectious and inflammatory diseases in adults and children older than 2 months, caused by microorganisms sensitive to cefepime with sulbactam: lower respiratory tract infections, including pneumonia and bronchitis; urinary tract, both complicated, including pyelonephritis, and uncomplicated; skin and soft tissues; abdominal cavity including peritonitis and biliary tract infections; organs of the small pelvis; septicemia; febrile neutropenia. Prevention of infections in the surgical site during abdominal surgery;
Shelf life: 3 years;

Marketing Authorization: ЛП-005253 dated 20.12.2018

Brief instructions for the medical use of Maxictam^®-AF

Pharmacotherapeutic group: antibiotic cephalosporin + beta-lactamase inhibitor.

Dosage form: powder for the preparation of a solution for intravenous and intramuscular administration.

Indications: infectious and inflammatory diseases in adults, caused by microorganisms sensitive to cefepime with sulbactam: lower respiratory tract infections, including pneumonia and bronchitis; infections of the urinary tract, both complicated, including pyelonephritis, and uncomplicated; infections of skin and soft tissues; abdominal cavity including peritonitis and biliary tract infections; inflammatory diseases of organs of the small pelvis; septicemia; febrile neutropenia. Prevention of infections in the surgical site during abdominal surgery; Infectious and inflammatory diseases in children older than 2 months caused by microorganisms sensitive to cefepime + sulbactam: pneumonia; urinary tract infections, both complicated, including pyelonephritis, and uncomplicated; infections of the skin and soft tissues; septicemia; febrile neutropenia; bacterial meningitis.

Contraindications: hypersensitivity to cefepime, as well as to other cephalosporins, penicillins, other beta-lactam antibiotics, arginine, sulbactam. Infancy under 2 months.

Administration and dosage: the drug is administered intravenously, intramuscularly. Doses and route of administration depend on the sensitivity of the pathogens, the severity of the infection, the state of renal function and the general condition of the patient. Intravenous administration is recommended for patients with severe or life-threatening infections, especially those at risk of septic shock. The drug can be administered as a bolus or infusion for at least 30 minutes. Adults and children weighing more than 40 kg with normal renal function: with mild to moderate severity (0.5-1 g IV or IM every 12 hours), severe infections (2 g IV every 12 hours). Patients receiving cefepime + sulbactam at the ratio 1:1 may require additional cefepime administration. Children over 2 months old with a body weight of up to 40 kg: for infections of the skin and soft tissues, urinary tract, pneumonia, the recommended dose is 50 mg/kg of cefepime every 12 hours for 10 days. In case of severe infections, every 8 hours. The recommended maximum daily dose of sulbactam is 4 g. The duration of treatment is on average 7-10 days.

Prescription status: Rx only.

Shelf life: 3 years. MA: ЛП-005253.